Tivoli is a town and comune in Lazio, central Italy, 30 kilometres north-east of Rome, at the falls of the Aniene river where it issues from the Sabiā¦Tivoli is a town and comune in Lazio, central Italy, 30 kilometres north-east of Rome, at the falls of the Aniene river where it issues from the Sabine Hills. The city offers a wide view over the Roman Campagna.