Margaret Qualley costars in this gory — like, really gory! — satire about beauty and aging The Substance, a corrosively vicious horror satire with a career-resuscitating turn by Demi Moore, begins with an inspired if not very kind joke: You’re looking down the Hollywood Walk of Fame as a fresh,

The new body-horror movie "The Substance" is a wild time, It also took co-stars Demi Moore and Margaret Qualley way out of their comfort zones.