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Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...
8 Department of Environmental Medicine and Public Health, Section of Occupational Medicine, University of Padova, Italy 9 Departments of Medicine, Oncology and Radiology, Section of Respiratory ...
Introduction and Objectives Cardiac arrhythmias are regularly found in patients with COPD, with higher frequencies reported during exacerbations. We wished to examine the impact of tachycardia and new ...
Objective Anaesthesiology guidelines suggest that opioids worsen obstructive sleep apnoea (OSA) despite no randomised controlled trial evidence. We therefore conducted a randomised controlled trial to ...
DST/NRF Centre of Excellence in Biomedical Tuberculosis Research and MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, ...
Background Haemodynamic measurements may be superior to the 6-min walk distance (6MWD) as outcome measures in pulmonary hypertension (PH) as they are directly linked to the mechanisms of disease and ...
1 Department of Pulmonary and Intensive Care Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands 2 Department of Biostatistics, Erasmus Medical Center Rotterdam Correspondence to: ...
Division of Respiratory and Critical Care Medicine, Department of Medicine, Queen’s University, Kingston, Ontario, Canada Correspondence to: Dr D E O’Donnell Division of Respiratory and Critical Care ...
Background The bronchial epithelium and underlying reticular basement membrane (RBM) have a close spatial and functional inter-relationship and are considered an epithelial–mesenchymal trophic unit ...
1 Department of Thoracic Surgery, School of Medicine, Akdeniz University, Antalya, Turkey 2 Department of Pathology, School of Medicine, Akdeniz University, Antalya, Turkey 3 Department of Histology ...
Background Carcinogen-inflicted human cancers, including lung tumours harbour thousands of mutations per genome, most of which are unknown (Garraway, LA et al, Cell 2013;153:17–37). Aim To develop a ...